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초록
Purpose: Time-based acoustic perturbation has limitations because it cannot accurately extract the cycle of voice signals in
non-periodic, rough, breathy voices. The purpose of this study is to compare the cepstral analysis between glottic cancer and
laryngeal leukoplakia. Methods: Fifty male glottic cancer patients and fifty male vocal fold leukoplakia patients were
evaluated. After their criteria were confirmed, signal analysis was performed using Analysis of Dysphonia in Speech and
Voice (ADSV) and SpeechTool software. This study confirmed the correlation of the cepstral measures and GRBAS scale.
Individuals were recorded reading a standard passage (′Sanchaek′) and sustaining the vowel /A/. Cepstral measures were
obtained for CPP (dB), L/H Spectral Ratio (dB), Mean CPP F0 (Hz), SpeechTool′s CPPs, and Mean CPP F0 (Hz). Statistical
analyses were applied to Independent-samples t-test in SPSS 19.0 and receiver operating characteristic in Med Calc. Results:
The results revealed a significant result on measures of CPP (dB), L/H Spectral Ratio (dB), and Mean CPP F0 (Hz) in both
groups. In a sample of glottic cancer speakers versus leukoplakia speakers, cepstral measures of CPP, L/H ratio, Mean CPP
F0 were able to differentiate these groups from one another in both sustained vowel phonation and continuous speech
contexts with high sensitivity and specificity. Conclusions: The results of this study support the growing body of literature
documenting the significant value of cepstral based acoustic measures to the clinical evaluation and management processes.
Keywords: Cepstral analysis, glottic cancer, laryngeal leukoplakia, ADSV, SpeechTool
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